Our World Commentary

One miscarriage is a disaster. Two is worse. Imagine the suffering of women who have 3, 5, 7 or even 12 pregnancy losses, and sometimes as late as the last few weeks of their pregnancy.

We now know that Hughes Syndrome is the most common treatable cause of recurrent miscarriage: depending on which study you quote, the figure is up to 1 in 5. Furthermore, late pregnancy loss, fortunately an unusual problem in pregnancy, is very strongly associated with Hughes Syndrome as is pre-eclampsia, placental abruption and intra-uterine growth restriction.

For the sake of a simple blood test, patients with miscarriage or late pregnancy loss can be tested for Hughes Syndrome. Treatment of these patients has proved one of the true successes of modern medicine, the successful pregnancy rate rising from a previous low of fewer than 20% to figures now in the region of 75-80% success rate. Treatment…

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